KMID : 0367219920090010113
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Sejong Medical Journal 1992 Volume.9 No. 1 p.113 ~ p.120
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Correlation between Esophageal Motility Disturbance and Inflammation in Patients of Alkaline Reflux Esophagitis following Total Gastrectomy
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¹è¼ø±â/±èÁ¤ÅÃ/ÃÖÀ±¹é/¼Áø¼®
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Abstract
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We performed esophageal manometry and endoscopy with biopsy of ten patients who had undergone total gastrectomy due to advanced stomach cancer in the high body (not involving GE junction or cardia) between 3 weeks and 2 year 3 months after
surgery.
The
study was undertaken to evaluate the esophageal motility disturbance and compare with the pathologic severity of esophagitis.
In nine cases, the primary peristalsis failed at the frequency of over 60%, and in 4 cases of which the failure rate was 100%. In these 4 cases severe submucosal inflammatory cell infiltration was observed, exhibiting positive correlation between
motility disturbance and histologic damage.
The types of failed primary peristalsis included no generation of peristalsis, simultaneous contractions and retrograde peristalsis. The retrograde peristalsis was observed in 4 cases, 3 cases of which exhibited sever histological inflammation as
well
as total failure in primary peristaltic sequence.
The exam results did not change during the period of 2 to 5 months of following check-up in 5 cases.
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